Chemical Name: (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)- 3,5,10,12,12a-pentahydroxy- 6-methyl- 1,11-dioxo- 1,4,4a,5,5a,6,11,12a-octahydrotetracene- 2-carboxamide hydrochloride hemiethanolate hemihydrate
Biological ActivityBroad-spectrum antibiotic and MMP inhibitor; tetracycline derivative. Increases and promotes smooth muscle cell adhesion; inhibits proliferation and migration. Protects the microvasculature by inhibiting plasminogen systems.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types.
Wernig et al.
Doxycycline alters vascular smooth muscle cell adhesion, migration, and reorganization of fibrillar collagen matrices.
Franco et al.
Doxycycline inhibits MMPs via modulation of plasminogen activators in focal cerebral ischemia.
Burggraf et al.
Citations for Doxycycline hyclate
The citations listed below are publications that use Tocris products. Selected citations for Doxycycline hyclate include:
2 Citations: Showing 1 - 2
Core Transcription Factors Promote Induction of PAX3-Positive Skeletal Muscle Stem Cells.
Authors: Sato Et al.
Stem Cell Reports 2019;13:352
Neurotrophic actions initiated by proNGF in adult sensory neurons may require peri-somatic glia to drive local cleavage to NGF.
Authors: Kalous Et al.
J Neurochem 2012;122:523
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for Doxycycline hyclate
Average Rating: 4 (Based on 1 Review)
Have you used Doxycycline hyclate?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Doxycycline was used to study its resistance pattern against Pseudomonas aeruginosa. E coli was used as a standard to compare.