DSR 6434

Catalog # Availability Size / Price Qty
4809/10
4809/50
Cat.No. 4809 - DSR 6434 | C19H28N8O2 | CAS No. 1059070-10-8
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Description: Potent TLR7 agonist

Chemical Name: 6-Amino-2-(butylamino)-9-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]methyl]-7,9-dihydro-8H-purin-8-one

Purity: ≥98%

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Biological Activity

Potent TLR7 agonist (EC50 = 7.2 nM). Activates several immune effector cells in vitro. Suppresses metastasis in vivo and enhances efficacy of radiation therapy in a model of colorectal carcinoma.

Technical Data

M.Wt:
400.48
Formula:
C19H28N8O2
Solubility:
Soluble to 50 mM in 1eq. HCl and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1059070-10-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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