DV 7028 hydrochloride

   
Product Datasheet
Catalog Number:4480
Chemical Name:3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2H-pyrido[1,2-a]-1,3,5-triazine-2,4(3H)-dione hydrochloride
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Biological Activity
Selective 5-HT2A receptor antagonist (Ki = 22 nM for at 5-HT2 receptors). Exhibits no affinity for 5-HT1A, 5-HT1B or 5-HT1D receptors. Inhibits collagen-induced serotonin secretion and platelet aggregation; displays no effect on serotonin uptake by platelets. Shown to inhibit arterial thrombus formation, but not venous thrombosis, in rat models.
Technical Data
  • M.Wt:
    436.91
  • Formula:
    C21H25FN4O3.HCl
  • Solubility:
    Soluble to 10 mM in water with gentle warming and to 10 mM in DMSO with gentle warming
  • Purity:
    >99
  • Storage:
    Desiccate at RT
  • CAS No:
    133364-62-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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VersaClone cDNA Plasmids
Description Application Cat# Citations Images  

Human 5-HT1D (NP_000855) VersaClone cDNA

RDC0285
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