Potent FXR antagonist (IC50
= 7.5 nM). Exhibits no detectable cytotoxicity in cell-based assays.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold under license from the Beckman Research Institute of the City of Hope.
Identification of trisubstituted-pyrazol carboxamide analogs as novel and potent antagonists of farnesoid X receptor.
Yu et al.