Chemical Name: (E)-3-Ferrocenylmethylidene-1,3-dihydro-2H-indol-2-one
Biological Activity Selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC50 = 214 nM). Displays anticancer activity (IC50< 1 μM against B16 murine melanoma lines). Does not significantly inhibit VEGFR1 or PDGFRa or b at a concentration of 10μM.
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