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Catalog Number:3883
Chemical Name:(Z)-3-Ferrocenylmethylidene-1,3-dihydro-2H-indol-2-one
Product Details
Supplemental Products
Reviews
Biological Activity
Selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC50 = 220 nM). Displays anticancer activity (IC50< 1 μM against B16 murine melanoma lines). Does not significantly inhibit VEGFR1 or PDGFRa or b at a concentration of 10μM.
Selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC50 = 220 nM). Displays anticancer activity (IC50< 1 μM against B16 murine melanoma lines). Does not significantly inhibit VEGFR1 or PDGFRa or b at a concentration of 10μM.
Geometric Isomer also available.
Technical Data
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M.Wt:329.17
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Formula:C19H15FeNO
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Solubility:Soluble to 5 mM in DMSO with gentle warming
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Storage:Store at +4°C
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CAS No:1137967-28-2
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Product Datasheets
Tocris Bioscience is the leading supplier of novel and exclusive tools for
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Tocris is a Bio-Techne brand.