Home / VEGF Receptor Inhibitors / (Z)-FeCP-oxindole

(Z)-FeCP-oxindole

3883 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3883/10
(Z)-FeCP-oxindole | CAS No. 1137967-28-2 | VEGF Receptor Inhibitors
1 Image
Description: Selective VEGFR-2 inhibitor

Chemical Name: (Z)-3-Ferrocenylmethylidene-1,3-dihydro-2H-indol-2-one

Product Details
Supplemental Products
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

Selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC50 = 220 nM). Displays anticancer activity (IC50< 1 μM against B16 murine melanoma lines). Does not significantly inhibit VEGFR1 or PDGFRa or b at a concentration of 10μM.

Geometric Isomer also available.

Technical Data

M.Wt:
329.17
Formula:
C19H15FeNO
Solubility:
Soluble to 5 mM in DMSO with gentle warming
Storage:
Store at +4°C
CAS No:
1137967-28-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Background References

  1. Synthesis and evaluation of metallocene containing methylene-1,3-dihydro-2H-indol-2-ones as kinase inhibitors
    Spencer et al.
    Metallomics, 2011;3:600
  2. Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones.
    Spencer et al.
    Dalton Transact., 2009;6:918

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

VersaClone cDNA Plasmids

Mouse VEGFR2/KDR/Flk-1 (NP_034742) VersaClone cDNA

RDC1823

Human VEGFR2/KDR/Flk-1 (AAC16450) VersaClone cDNA

RDC0467

Reviews for (Z)-FeCP-oxindole

There are currently no reviews for this product. Be the first to review (Z)-FeCP-oxindole and earn rewards!

Have you used (Z)-FeCP-oxindole?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.