EB 47

Catalog # Availability Size / Price Qty
4140/10
4140/50
Poly(ADP-ribose) Polymerase Inhibitors Small Molecule
1 Image
Description: Potent PARP-1 inhibitor

Chemical Name: 5'-Deoxy-5'-[4-[2-[(2,3-Dihydro-1-oxo-1H-isoindol-4-yl)amino]-2-oxoethyl]-1-piperazinyl]-5'-oxoadenosine dihydrochloride

Purity: ≥99%

Product Details
Citations (3)
Reviews

Biological Activity

Potent inhibitor of PARP-1 (IC50 = 45 nM). Reduces infarct volume in both a rat transient middle cerebral arterial occlusion model and a cardiac reperfusion model.

Technical Data

M.Wt:
610.45
Formula:
C24H27N9O6.2HCl
Solubility:
Soluble to 5 mM in water with gentle warming and to 50 mM in DMSO
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
1190332-25-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for EB 47

The citations listed below are publications that use Tocris products. Selected citations for EB 47 include:

3 Citations: Showing 1 - 3

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