Glutathione peroxidase mimic; peroxynitrite scavenger. Inhibits lipoxygenase, cyclooxygenase, nitric oxide synthase, protein kinase C and H+
-ATPase activity. Inhibits the hepatic carcinogenic effects of aflatoxin B1
. Antioxidant and anti-inflammatory.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Molecular actions of ebselen--an antiinflammatory antioxidant.
Inhibition of ebselen on aflatoxin B(1)-induced hepatocarcinogenesis in Fischer 344 rats.
Yang et al.
Kinetic studies of the radical-scavenging activity of ebselen, a seleno-organic compound.
Fujisawa and Kadoma
Anticancer Res., 2005;25:3989