EDA-A2, a product of the EDA gene (also known as Tabby), is a type II transmembrane protein that is a member of the TNF superfamily. Human EDA-A2 is a 389 amino acid (aa) protein with a predicted N-terminal 39 aa cytoplasmic domain, a 22 aa transmembrane domain and a C-terminal 328 aa extracellular domain.
EDA-A2/Ectodysplasin A2 Antibody [DyLight 350]
Novus Biologicals | Catalog # AF922D
Key Product Details
Species Reactivity
Human
Applications
Blockade of Receptor-ligand Interaction
Label
DyLight 350 (Excitation = 353 nm, Emission = 432 nm)
Antibody Source
Polyclonal Goat IgG
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human EDA‑A2/Ectodysplasin A2
Ala179-Ser389
Accession # NP_001005609
Ala179-Ser389
Accession # NP_001005609
Specificity
Detects human EDA‑A2/Ectodysplasin A2 in direct ELISAs and Western blots. In Western blots, less than 10% cross-reactivity with recombinant human (rh) APRIL, rhBAFF, rhLIGHT, rhOX40 Ligand, and rhTRAIL is observed and less than 2% cross‑reactivity with recombinant mouse EDA, rhTNF-alpha, rhVEGI, rhGITR Ligand, and rhFasLigand is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for EDA-A2/Ectodysplasin A2 Antibody [DyLight 350]
Application
Recommended Usage
Blockade of Receptor-ligand Interaction
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: EDA-A2/Ectodysplasin A2
Alternate Names
EDAA2
Gene Symbol
EDA
Additional EDA-A2/Ectodysplasin A2 Products
Product Documents for EDA-A2/Ectodysplasin A2 Antibody [DyLight 350]
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for EDA-A2/Ectodysplasin A2 Antibody [DyLight 350]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Associated Pathways
