A radical scavenger and antioxidant which is able to protect against the effects of ischemia, probably by inhibiting the lipoxygenase system. Protects against MPTP-induced neurotoxicity.
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Effects of a novel free radical scavenger, MC-186, on ischemic brain damage in rat distal middle cerebral artery occlusion model.
Kawai et al.
Edaravone (3methyl-1-phenyl-2-pyrazolin-5-one), a radical scavenger, prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the substantia nigra but not the striatum.
Kawasaki et al.
Protective effects of MCI-186 on cerebral ischemia: possible involvement of free radical scavenging and antioxidant actions.
Watanabe et al.
The citations listed below are publications that use Tocris products. Selected citations for Edaravone include:
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