Chemical Name: erythro-9-(2-Hydroxy-3-nonyl)adenine hydrochloride
Biological Activity Selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 μM). Also a potent inhibitor of adenosine deaminase. Suppresses spontaneous differentiation of human ESCs in feeder-free conditions. Also prevents directed neuronal differentiation.
Soluble to 100 mM in water and to 100 mM in ethanol and to 100 mM in DMSO
Store at RT
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