EHNA hydrochloride

  ( 7 citations )    
Product Datasheet
Catalog Number:1261
Chemical Name:erythro-9-(2-Hydroxy-3-nonyl)adenine hydrochloride
Product Details
Citations (7)
Reviews
Biological Activity
Selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 μM). Also a potent inhibitor of adenosine deaminase. Suppresses spontaneous differentiation of human ESCs in feeder-free conditions. Also prevents directed neuronal differentiation.
Technical Data
  • M.Wt:
    313.83
  • Formula:
    C14H23N5O.HCl
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in ethanol and to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    58337-38-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for EHNA hydrochloride include:

7 Citations: Showing 1 - 7
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  1. Alkaline Phosphatase, Soluble Extracellular Adenine Nucleotides, and Adenosine Production after Infant Cardiopulmonary Bypass
    Authors: Davidson Et al.
    PLoS One  2016;11:e0158981
  2. Inhibition of adenosine deaminase (ADA)-mediated metabolism of cordycepin by natural substances.
    Authors: Li Et al.
    Am J Physiol Renal Physiol  2015;3:e00121
  3. Detection of oxidation products of 5-methyl-2'-deoxycytidine in Arabidopsis DNA.
    Authors: Liu Et al.
    Nat Neurosci  2014;8:e84620
  4. Induction of 8,5'-cyclo-2'-deoxyadenosine and 8,5'-cyclo-2'-deoxyguanosine in isolated DNA by Fenton-type reagents.
    Authors: Guerrero Et al.
    Chem Res Toxicol  2013;26:1361
  5. Modulation of bladder function by luminal adenosine turnover and A1 receptor activation.
    Authors: Prakasam Et al.
    PLoS One  2012;303:F279
  6. Adenosine and inosine release during hypoxia in the isolated spinal cord of neonatal rats.
    Authors: Takahashi Et al.
    Br J Pharmacol  2010;161:1806
  7. Characterization and functional relevance of cyclic nucleotide phosphodiesterase isoenzymes of the human prostate.
    Authors: Uckert
    J Urol  2001;166:2484

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