receptor agonist (EC50
= 1.0 nM) that displays selectivity over other 5-HT receptors (IC50
values are 7.4, 110, 180, 240, 450, 620, 660 and 3000 nM for 5-HT6
receptors respectively). Shows moderate affinity at 5-HT3
= 34 nM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists.
Mattsson et al.
The citations listed below are publications that use Tocris products. Selected citations for EMD 386088 hydrochloride include:
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