Catalog Number: 1162
Alternate Names: ET-3
Biological Activity
Endogenous neuropeptide and potent vasoconstrictor. Displays selectivity for the putative ETC endothelin receptor.
Technical Data
  • M.Wt:
    2643
  • Formula:
    C121H168N26O33S4
  • Sequence:
    CTCFTYKDKECVYYCHLDIIW

    (Modifications: Disulfide bridge between 1 - 15, 3 - 11)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    117399-93-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.
    Inoue et al.
    Proc.Natl.Acad.Sci.U.S.A., 1989;86:2863
  2. Involvement of ETA and ETB receptors in the activation of phospholipase D by endothelins in cultured rat cortical astrocytes.
    Servitja et al.
    Br.J.Pharmacol., 1998;124:1728
  3. Molecular biology and biochemistry of the endothelins.
    Yanagisawa and Masaski
    TiPS, 1989;10:374
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Endothelin 3 (human, rat) include:

1 Citations: Showing 1 - 1

  1. Pharmacological characterization of endothelin receptors-mediated contraction in the mouse isolated proximal and distal colon.
    Authors: Khan Et al.
    Br J Pharmacol 2006;147:607
Average Rating: 4 (Based on 1 review)

Have you used Endothelin 3 (human, rat)?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Read what people are saying who have used Endothelin 3 (human, rat).

Filter by Ratings
Very Good
(1)
All Ratings
Filter by Applications
All Applications
Filter by Species
All Species

Images Ratings Applications Species Reviewed By Date Details
  Very Good
  Anonymous 12/05/2017
Show

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information