Endothelin 3 (human, rat)
Tocris Bioscience | Catalog # 1162
Potent vasoconstrictor
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Key Product Details
Description
Potent vasoconstrictor
Alternative Names
ET-3
Product Description
Endothelin 3 (human, rat) is an endogenous neuropeptide and potent vasoconstrictor. Displays selectivity for the putative ETC endothelin receptor.
Product Specifications for Endothelin 3 (human, rat)
Molecular Weight
2643.00
Formula
C121H168N26O33S4
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
117399-93-6
PubChem ID
16133809
InChI Key
OQGZWNZGVYLIFX-JQWUVQPESA-N
SMILES
[H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@@H](NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@@H](NC1=O)[C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.
- Servitja Involvement of ETA and ETB receptors in the activation of phospholipase D by endothelins in cultured rat cortical astrocytes. Br.J.Pharmacol. 1998 PMID: 9756390
- Yanagisawa and Masaski Molecular biology and biochemistry of the endothelins. TiPS 1989 PMID: 2690429
- Inoue The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc.Natl.Acad.Sci.U.S.A. 1989 PMID: 2649896
Product Documents for Endothelin 3 (human, rat)
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Endothelin 3 (human, rat)
For research use only
Citations for Endothelin 3 (human, rat)
Customer Reviews for Endothelin 3 (human, rat) (1)
4 out of 5
1 Customer Rating
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Assay Type: In VitroCell Line/Tissue: iPSCVerified Customer | Posted 12/05/2017Used at 100nM for deriving human melanocytes from iPSC cultures.
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