Catalog Number: 1162
Alternate Names: ET-3
Biological Activity
Endogenous neuropeptide and potent vasoconstrictor. Displays selectivity for the putative ETC endothelin receptor.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Disulfide bridge between 1 - 15, 3 - 11)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.
    Inoue et al.
    Proc.Natl.Acad.Sci.U.S.A., 1989;86:2863
  2. Involvement of ETA and ETB receptors in the activation of phospholipase D by endothelins in cultured rat cortical astrocytes.
    Servitja et al.
    Br.J.Pharmacol., 1998;124:1728
  3. Molecular biology and biochemistry of the endothelins.
    Yanagisawa and Masaski
    TiPS, 1989;10:374

The citations listed below are publications that use Tocris products. Selected citations for Endothelin 3 (human, rat) include:

Showing Results 1 - 1 of 1

  1. Pharmacological characterization of endothelin receptors-mediated contraction in the mouse isolated proximal and distal colon.
    Authors: Khan Et al.
    Br J Pharmacol
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