Endothelin 3 (human, rat)
Biological ActivityEndothelin 3 (human, rat) is an endogenous neuropeptide and potent vasoconstrictor. Displays selectivity for the putative ETC endothelin receptor.
(Modifications: Disulfide bridges:1-15, 3-11)
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The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.
Inoue et al.
Involvement of ETA and ETB receptors in the activation of phospholipase D by endothelins in cultured rat cortical astrocytes.
Servitja et al.
Molecular biology and biochemistry of the endothelins.
Yanagisawa and Masaski
Citation for Endothelin 3 (human, rat)
The citations listed below are publications that use Tocris products. Selected citations for Endothelin 3 (human, rat) include:
1 Citation: Showing 1 - 1
Pharmacological characterization of endothelin receptors-mediated contraction in the mouse isolated proximal and distal colon.
Authors: Khan Et al.
Br J Pharmacol 2006;147:607
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Used at 100nM for deriving human melanocytes from iPSC cultures.