ER 50891

  ( 3 citations )    
Product Datasheet
Catalog Number:3823
Chemical Name:4-[5-[8-(1-Methylethyl)-4-phenyl-2-quinolinyl]-1H-pyrrolo-2-benzoic acid
Product Details
Citations (3)
Reviews
Biological Activity
Antagonist of RARα receptors (IC50 = 31.2 nM). Displays selective affinity for RARα (relative IC50 values are 1.8, 432 and 535 nM for RARα, RARγ and RARβ respectively).
Technical Data
  • M.Wt:
    432.51
  • Formula:
    C29H24N2O2
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    187400-85-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for ER 50891 include:

3 Citations: Showing 1 - 3
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  1. Diverse feather shape evolution enabled by coupling anisotropic signalling modules with self-organizing branching programme.
    Authors: Li Et al.
    Nat Commun  2017;8:ncomms14139
  2. Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression.
    Authors: Centritto Et al.
    J Reprod Dev  2015;7:950
  3. Additive Effects of Retinoic Acid (RA) and Bone Morphogenetic Protein 4 (BMP-4) Apoptosis Signaling in Retinoblastoma Cell Lines.
    Authors: Müller Et al.
    PLoS One  2015;10:e0131467

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