Erastin

Catalog # Availability Size / Price Qty
5449/10
Cat.No. 5449 - Erastin | C30H31ClN4O4 | CAS No. 571203-78-6
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Description: Mitochondrial VDAC modulator; also Ferroptosis activator

Chemical Name: 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone

Purity: ≥98%

Product Details
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Biological Activity

Antitumor agent; selective for cells expressing oncogenic RAS. Also Ferroptosis activator; induces oxidative, non-apoptotic cell death in tumors by modulating mitochondrial voltage-dependent anion channels (VDAC). Cell permeable.

Technical Data

M.Wt:
547.04
Formula:
C30H31ClN4O4
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
571203-78-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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