ESI 05

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ESI 05 | CAS No. 5184-64-5 | EPAC Inhibitors
1 Image
Description: Epac2 inhibitor

Chemical Name: 1,3,5-Trimethyl-2-[(4-methylphenyl)sulfonyl]benzene

Purity: ≥98%

Product Details

Biological Activity

ESI 05 is an EPAC2 inhibitor. Inhibits cAMP binding to EPAC2 and cAMP mediated EPAC2 guanine nucleotide exchange factor (GEF) activity (IC50 = 0.4 μM).

Technical Data

Soluble to 100 mM in DMSO and to 100 mM in ethanol
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Isoform-specific antagonists of exchange proteins directly activated by cAMP.
    Tsalkova et al.
    Proc.Natl.Acad.Sci.USA., 2012;109:18613

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