Ethyl LipotF

Catalog # Availability Size / Price Qty
5950/10
Ethyl LipotF | CAS No. 1808089-27-1 | Other Oxidase/Oxygenase Compounds
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Description: Selective FTO inhibitor

Chemical Name: Ethyl (E)-4-(2-(4-benzylnicotinoyl)hydrazinyl)-4-oxobut-2-enoate

Purity: ≥98%

Product Details
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Biological Activity

Selective FTO inhibitor (IC50 = 0.81 μM). Exhibits >30-fold selectivity for FTO over ALKBH2, 3 and 5 and >100-fold selectivity over PHD2 and JMJD2A. Increases levels of modified N6-methyladenosine (m6A) in HeLa cells in a concentration-dependent manner.

Technical Data

M.Wt:
353.38
Formula:
C19H19N3O4
Solubility:
Soluble to 20 mM in ethanol and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1808089-27-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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