Chemical Name: 3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamide hydrochloride
Biological ActivityEticlopride hydrochloride is a selective dopamine D2/D3 receptor antagonist (Ki values are 0.50 and 0.16 nM respectively). Antipsychotic.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Some in vitro receptor binding properties of [3H]eticlopride, a novel substituted benzamide, selective for DA-D2 receptors in the rat brain.
Hall et al.
Involvement of DA receptors in the antipsychotic profile of (-) eticlopride.
Giuliani and Ferrari
The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys.
Claytor et al.
Citations for Eticlopride hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Eticlopride hydrochloride include:
7 Citations: Showing 1 - 7
Polysynaptic inhibition between striatal cholinergic interneurons shapes their network activity patterns in a dopamine-dependent manner.
Authors: Dorst Et al.
Nat Commun 2020;11:5113
A DA receptor contributes to paraquat-induced neurotoxicity in Drosophila.
Authors: Cassar Et al.
J Ginseng Res 2015;24:197
Effects of DA D2-Like Receptor Antagonists on Light Responses of Ganglion Cells in Wild-Type and P23H Rat Retinas.
PLoS One 2015;10:e0146154
DA in the dorsal hippocampus impairs the late consolidation of cocaine-associated memory.
Authors: Kramar Et al.
Int J Neuropsychopharmacol 2014;39:1645
Korean Red Ginseng attenuates anxiety-like behavior during ethanol withdrawal in rats.
Authors: Zhao Et al.
Functional integration of grafted neural stem cell-derived DArgic neurons monitored by optogenetics in an in vitro Parkinson model.
Authors: Tønnesen Et al.
PLoS One 2011;6:e17560
DArgic regulation of sleep and cataplexy in a murine model of narcolepsy.
Authors: Burgess Et al.
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At a dose that did not alter responding during food self-administration (6.0 micrograms/kg), systemic injections of eticlopride significantly increased responding during cue-induced reinstatement of food seeking tests.