Eticlopride hydrochloride

Tocris Bioscience | Catalog # 1847

D2 and D3 antagonist (D3 > D2)
Tocris Bioscience

Key Product Details

Description

D2 and D3 antagonist (D3 > D2)

Alternative Names

(-)-Eticlopride
View all Non-selective Dopamine Receptor Antagonists »

Product Description

Eticlopride hydrochloride is a selective dopamine D2/D3 receptor antagonist (Ki values are 0.50 and 0.16 nM respectively). Antipsychotic.

Product Specifications for Eticlopride hydrochloride

Molecular Weight

377.31

Formula

C17H25ClN2O3.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamide hydrochloride

CAS Number

97612-24-3

PubChem ID

57266

InChI Key

HFJFXXDHVWLIKX-YDALLXLXSA-N

SMILES

O=C(C2=C(OC)C(Cl)=CC(CC)=C2O)NC[C@@H]1CCCN1CC.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 37.73 100

Preparing Stock Solutions for Eticlopride hydrochloride

The following data is based on the product molecular weight 377.31.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.65 mL 13.25 mL 26.50 mL
5 mM 0.53 mL 2.65 mL 5.30 mL
10 mM 0.27 mL 1.33 mL 2.65 mL
50 mM 0.05 mL 0.27 mL 0.53 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 29 publications citing the usage of this product.

Product Documents for Eticlopride hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Eticlopride hydrochloride

For research use only

Citations for Eticlopride hydrochloride

Customer Reviews for Eticlopride hydrochloride (1)

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  • Effects of eticlopride on cue-induced reinstatement of food seeking
    Name: Kevin Ball
    Species: Rat
    Assay Type: In Vivo
    Verified Customer | Posted 01/22/2019
    At a dose that did not alter responding during food self-administration (6.0 micrograms/kg), systemic injections of eticlopride significantly increased responding during cue-induced reinstatement of food seeking tests.
    Eticlopride hydrochloride 1847

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