Chemical Name: 4-[(3aR,4R,7S,7aS-rel)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide
Biological ActivityNegative control for endo-IWR 1 25-fold less active than endo-IWR 1; exhibits decreased activity against the Wnt/β-catenin pathway.
Active Analog also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Structure-activity relationship studies of small-molecule inhibitors of Wnt response.
Lu et al.
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer.
Chen et al.
Nature Chem.Biol., 2008;5:100
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Tocris Small Molecules
VersaClone cDNA Plasmids
Reviews for exo-IWR 1
There are currently no reviews for this product. Be the first to review exo-IWR 1 and earn rewards!
Have you used exo-IWR 1?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image