exo-IWR 1

Tocris Bioscience | Catalog # 3947

Negative control for endo-IWR 1 (Cat. No. 3532)
Tocris Bioscience
Discontinued Product
3947 has been discontinued. View all beta-Catenin Compounds products.

Key Product Details

Description

Negative control for endo-IWR 1 (Cat. No. 3532)
View all beta-Catenin Compounds »

Product Description

exo

-IWR 1 is a negative control for endo-IWR 1 25-fold less active than endo-IWR 1; exhibits decreased activity against the Wnt/β-catenin pathway.

Active Analog also available.

Product Specifications for exo-IWR 1

Molecular Weight

409.44

Formula

C25H19N3O3

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

4-[(3aR,4R,7S,7aS-rel)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide

CAS Number

1127442-87-8

PubChem ID

1163034

InChI Key

ZGSXEXBYLJIOGF-BTYSMDAFSA-N

SMILES

O=C(NC5=CC=CC6=C5N=CC=C6)C(C=C4)=CC=C4N2C([C@@]1([H])[C@@H](C3)C=C[C@@H]3[C@]([H])1C2=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 40.94 100

Preparing Stock Solutions for exo-IWR 1

The following data is based on the product molecular weight 409.44.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.44 mL 12.21 mL 24.42 mL
5 mM 0.49 mL 2.44 mL 4.88 mL
10 mM 0.24 mL 1.22 mL 2.44 mL
50 mM 0.05 mL 0.24 mL 0.49 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for exo-IWR 1

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for exo-IWR 1

For research use only

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