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Description: Fluorescent HIF-1α peptide; can be used to evaluate the effect of VHL binding on degradation activity

Purity: ≥95%

Product Details

Biological Activity

FAM-DEALA-Hyp-YIPD is a fluorescent HIF-1α peptide (Kd = 180-560 nM). Can be used to assess VHL binding in Fluorescence Polarization (FP) displacement assay, and evaluate the effect of VHL binding on degradation activity. Excitation maximum = 485 nm, emission maximum = 535 nm. Longer peptide version, FAM-DEALAHypYIPMDDDFQLRSF (Cat. No. 7452), also available.

Optical Data for FAM-DEALA-Hyp-YIPD

Emission Color Green
λabs 485 nm
λem 520 nm
Closest Laser line 488 nm
Application Fluorescence Polarization (FP) Displacement Assays

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Technical Data


(Modifications: Asp-1 = 5-FAM-Asp, X-6 = Hyp)

Soluble to 1 mg/ml in 0.01M PBS
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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