Febuxostat

  ( 2 citations )    
Product Datasheet
Catalog Number:4427
Alternate Names:TEI 6720, TMX 67
Chemical Name:2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid
Product Details
Citations (2)
Reviews
Biological Activity
Non-purine inhibitor of xanthine oxidase (Ki = 1.2 nM). Binds to a channel leading to the enzyme active site; obstructs substrate binding.
Technical Data
  • M.Wt:
    316.37
  • Formula:
    C16H16N2O3S
  • Solubility:
    Soluble to 75 mM in DMSO and to 50 mM in ethanol
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    144060-53-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Febuxostat include:

2 Citations: Showing 1 - 2
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  1. Febuxostat improves outcome in a rat model of cancer cachexia.
    Authors: Konishi Et al.
    Front Cell Neurosci  2015;6:174
  2. Estradiol shapes auditory processing in the adult brain by regulating inhibitory transmission and plasticity-associated gene expression.
    Authors: Tremere Et al.
    J Neurosci  2009;29:5949

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