FFN 102 mesylate
Chemical Name: 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one methanesulfonate
Biological ActivityFFN 102 mesylate is a pH responsive fluorescent false neurotransmitter (FFN). Selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
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Fluorescent DA tracer resolves individual DArgic synapses and their activity in the brain.
Rodriguez et al.
Visualizing neurotransmitter secretion at individual synapses.
Sames et al.
ACS Chem.Neurosci., 2013;4:648
Development of pH-responsive fluorescent false neurotransmitters.
Lee et al.
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