FFN 102 mesylate
Chemical Name: 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one methanesulfonate
Biological ActivitypH responsive fluorescent false neurotransmitter (FFN). Selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Fluorescent dopamine tracer resolves individual dopaminergic synapses and their activity in the brain.
Rodriguez et al.
Visualizing neurotransmitter secretion at individual synapses.
Sames et al.
ACS Chem.Neurosci., 2013;4:648
Development of pH-responsive fluorescent false neurotransmitters.
Lee et al.
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