pH responsive fluorescent false neurotransmitter (FFN). Selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake.
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Fluorescent dopamine tracer resolves individual dopaminergic synapses and their activity in the brain.
Rodriguez et al.
Visualizing neurotransmitter secretion at individual synapses.
Sames et al.
ACS Chem.Neurosci., 2013;4:648
Development of pH-responsive fluorescent false neurotransmitters.
Lee et al.