FFN 270

Catalog # Availability Size / Price Qty
FFN 270 | CAS No. 2341841-05-0 | Fluorescent Transporter Probes
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Description: Fluorescent substrate for NET and VMAT2

Chemical Name: 3-(2-Aminoethyl)-8-fluoro-7-hydroxy-2H-chromen-2-one hydrochloride

Purity: ≥98%

Product Details

Biological Activity

FFN 270 is a fluorescent false neurotransmitter (FFN). Fluorescent substrate for NET and VMAT2. Labels noradrenergic neurons and their synaptic vesicles, and enables imaging of synaptic vesicle content release from specific axonal sites in vivo. Selectively labels NA neurons over other monoamine and CNS targets. Exhibits two resolved absorption/excitation maxima depending on solvent pH (excitation maxima: 320 nm or 365 nm, emission maxima: 475 nm).

Amphetamine-stimulated release of FFN 270 from noradrenergic projections

Amphetamine releases FFN 270 from noradrenergic projections in vivo. The video shows FFN 270 puncta in Layer 1 of the barrel cortex in mice taken before and after injection of amphetamine (AMPH).

Technical Data

Soluble to 100 mM in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of Columbia University.

Product Datasheets

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