FG 7142

  ( 4 citations )    
Product Datasheet
Catalog Number:0554
Chemical Name:N-Methyl-β-carboline-3-carboxamide
Product Details
Citations (4)
Reviews
Biological Activity
Inverse agonist and anxiogenic agent. Increases tyrosine hydroxylation and causes upregulation of β-adrenoceptors in mouse cerebral cortex.
Technical Data
  • M.Wt:
    225.25
  • Formula:
    C13H11N3O
  • Solubility:
    Soluble to 75 mM in 1eq. HCl and to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    78538-74-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for FG 7142 include:

4 Citations: Showing 1 - 4
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  1. Post-weaning social isolation of female rats, anxiety-related behavior, and serotonergic systems.
    Authors: Lukkes Et al.
    Brain Res  2012;1443:1
  2. Orexin 1 receptors are a novel target to modulate panic responses and the panic brain network.
    Authors: Johnson Et al.
    Life Sci  2012;107:733
  3. Post-weaning social isolation attenuates c-Fos expression in GABAergic interneurons in the basolateral amygdala of adult female rats.
    Authors: Lukkes Et al.
    Physiol Behav  2012;107:719
  4. The anxiogenic drug FG7142 increases self-injurious behavior in male rhesus monkeys (Macaca mulatta).
    Authors: Major Et al.
    J Neurosci  2009;85:753

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