FGIN-1-43
Discontinued Product
Chemical Name: N,N-Dihexyl-2-(4-chlorophenyl)-5-chloroindole-3-acetamide
Purity: ≥98%
Biological Activity
Most active of the 2-aryl-3-indoleacetamides; a new class of potent and specific ligands as probes for the mitochondial DBI receptor (peripheral benzodiazepine receptor).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Chemistry, binding affinities, and behavioural properties of a new class of "antineophobic" mitochondrial DBI receptor (mDRC) ligands.
Kozikowski et al.
J.Med.Chem., 1993;36:2908 -
2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR).
Romeo et al.
J.Pharmacol.Exp.Ther., 1992;262:971
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