FIN 56

Key Product Details

Product Description

FIN 56 is a bifunctional inducer of ferroptosis in vitro. Activates squalene synthase (SQS) leading to coenzyme Q₁₀ depletion. Also induces degradation of glutathione peroxidase 4 (GPX4), via acetyl-CoA carboxylase (ACC).

Product Specifications for FIN 56

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for FIN 56

The following data is based on the product molecular weight 517.66.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.93 mL	9.66 mL	19.32 mL
5 mM	0.39 mL	1.93 mL	3.86 mL
10 mM	0.19 mL	0.97 mL	1.93 mL
50 mM	0.04 mL	0.19 mL	0.39 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Cotto-Rios and Gavathiotis Chemical genetics: Unraveling cell death mysteries. Nat.Chem.Biol. 2016 PMID: 27315536
• Shimada Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis. Nat.Chem.Biol. 2016 PMID: 27159577

Product Documents for FIN 56