Potent phosholipase D (PLD) inhibitor (IC50
values are 20 and 25 nM for PLD2
respectively). Ameliorates PLD2
-driven suppression of membrane ruffling and cell spreading. Orally available.
Soluble to 50 mM in DMSO
Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Optimization of halopemide for phospholipase D2 inhibition.
Monovich et al.
5-fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis.
Su et al.
The citations listed below are publications that use Tocris products. Selected citations for FIPI include:
Showing Results 1 - 1 of 1