Found in Inflammatory Zone 1 (FIZZ1), also known as Resistin-like Molecule (RELM) alpha, is a cysteine-rich secreted protein that is a member of the FIZZ/RELM family. It is 111 amino acids (aa) in length, with aa 1-23 serving as a putative signal peptide. Mouse FIZZ1/RELM alpha has a predicted molecular weight of approximately 9.5 kDa, and shares 50% aa sequence identity with the human ortholog. FIZZ1/RELM alpha is expressed in white adipose tissue, but not in preadipocytes nor 3T3-L1 adipocytes. It is also expressed in lung tissue, and its expression has been seen to increase during allergic pulmonary inflammation. FIZZ1/RELM alpha has also been detected in the mammary glands, heart, tongue, skeletal muscles, and alternatively-activated macrophages.
FIZZ1/RELM alpha Antibody [FITC]
Novus Biologicals | Catalog # AF1523F
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot
Label
FITC (Excitation = 495 nm, Emission = 519 nm)
Antibody Source
Polyclonal Goat IgG
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Product Specifications
Immunogen
E. coli-derived recombinant mouse FIZZ1/RELM alpha
Asp24-Ser111
Accession # Q9EP95
Asp24-Ser111
Accession # Q9EP95
Specificity
Detects mouse FIZZ1/RELM alpha in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross‑reactivity with recombinant mouse Resistin is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for FIZZ1/RELM alpha Antibody [FITC]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: FIZZ1/RELM alpha
Long Name
Found in Inflammatory Zone 1/Resistin-like Molecule alpha
Alternate Names
RELM alpha, RETNLA, RETNLB
Gene Symbol
RETNLA
Additional FIZZ1/RELM alpha Products
Product Documents for FIZZ1/RELM alpha Antibody [FITC]
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for FIZZ1/RELM alpha Antibody [FITC]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
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