Mouse FIZZ1/RELM alpha Antibody

Catalog # Availability Size / Price Qty
AF1523
AF1523-SP
Product Details
Citations (5)
FAQs
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Mouse FIZZ1/RELM alpha Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse FIZZ1/RELM alpha in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross‑reactivity with recombinant mouse Resistin is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant mouse FIZZ1/RELM alpha
Asp24-Ser111
Accession # Q9EP95
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse FIZZ1/RELM alpha

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: FIZZ1/RELM alpha

RELM alpha, also known as ‘found in inflammatory zone 1’ (FIZZ1) belongs to the RELM1/FIZZ family of cysteine rich secretory proteins. RELM alpha is most abundantly expressed in white adipose tissue but not in preadipocytes nor 3T3-L1 adipocytes. RELM alpha expression is also detected in heart, lung, and tongue (1).

References
  1. Steppan, C.M. et al. (2001) Proc. Natl. Acad. Sci. USA 98:502.
Long Name
Found in Inflammatory Zone 1/Resistin-like Molecule alpha
Entrez Gene IDs
84666 (Human); 57262 (Mouse)
Alternate Names
1810019L16Rik; FIZZ1; Fizz-1; HIMF; RELM alpha; RELMa; RELMalpha; RELM-alpha; Retnla resistin like alpha; RETNLA; RETNLB; Xcp2

Product Datasheets

Citations for Mouse FIZZ1/RELM alpha Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

5 Citations: Showing 1 - 5
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  1. MEK1/2 Inhibition Promotes Macrophage Reparative Properties
    Authors: Matthew E Long
    J. Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  2. Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) in chronic hypoxia- and antigen-mediated pulmonary vascular remodeling.
    Authors: Angelini D, Su Q, Yamaji-Kegan K, Fan C, Skinner J, Poloczek A, El-Haddad H, Cheadle C, Johns R
    Respir Res, 2013;14(0):1.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  3. Choosing the right antibody for resistin-like molecule (RELM/FIZZ) family members.
    Authors: Fan C, Johns B, Su Q, Kolosova I, Johns R
    Histochem Cell Biol, 2012;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  4. Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) increases lung inflammation and activates pulmonary microvascular endothelial cells via an IL-4-dependent mechanism.
    Authors: Yamaji-Kegan K, Su Q, Angelini DJ, Myers AC, Cheadle C, Johns RA
    J. Immunol., 2010;185(9):5539-48.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  5. Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELM{alpha}) induces the vascular and hemodynamic changes of pulmonary hypertension.
    Authors: Angelini DJ, Su Q, Yamaji-Kegan K, Fan C, Skinner JT, Champion HC, Crow MT, Johns RA
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(4):L582-93.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC-P

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Secondary Antibodies

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