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Fluorobexarotene

4064 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4064/10
Fluorobexarotene | CAS No. 1190848-23-7 | Retinoid X Receptor Agonists
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Description: RXR agonist

Chemical Name: 2-Fluoro-4-[1-(5-,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid

Purity: ≥97%

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Biological Activity

Fluorobexarotene is a RXR agonist (Ki = 12 nM; EC50 = 43 nM at RXRα receptors). Displays similar RAR agonist activity to bexarotene; exhibits an apparent RXR binding affinity 75% greater than bexarotene.

Technical Data

M.Wt:
366.47
Formula:
C24H27FO2
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Purity:
≥97%
Storage:
Store at +4°C
CAS No:
1190848-23-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Manufactured and sold under license from Arizona State University - Patent Pending

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