Catalog Number: 4057
Chemical Name: 4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride
Biological Activity
Antipsychotic drug. Exhibits antagonistic activity at dopamine D1-5 receptors. Used in schizophrenia treatment.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water and to 50 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
  • This compound is a mixture of E/Z isomers (ratio: 60:40)
Background References
  1. Pharmacological properties of new antipsychotic agents: Use of animal models.
    Peuch et al.
    Neuropharmacology, 1981;20:1279

The citations listed below are publications that use Tocris products. Selected citations for Flupenthixol dihydrochloride include:

Showing Results 1 - 3 of 3

  1. A critical role for the Drosophila dopamine D1-like receptor Dop1R2 at the onset of metamorphosis.
    Authors: Regna Et al.
    PLoS One
  2. A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response.
    Authors: FitzGerald Et al.
    PLoS One
  3. First and second generation antipsychotics influence hippocampal gamma oscillations by interactions with 5-HT3 and D3 receptors.
    Authors: Schulz Et al.
    Br J Pharmacol
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