Chemical Name: 4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride
Biological ActivityFlupenthixol dihydrochloride is an antipsychotic drug. Exhibits antagonistic activity at dopamine D1-5 receptors. Used in schizophrenia treatment.
This compound is a mixture of E/Z isomers (ratio: 60:40).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
- This compound is a mixture of E/Z isomers (ratio: 60:40)
Pharmacological properties of new antipsychotic agents: Use of animal models.
Peuch et al.
Citations for Flupenthixol dihydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Flupenthixol dihydrochloride include:
3 Citations: Showing 1 - 3
A critical role for the Drosophila DA D1-like receptor Dop1R2 at the onset of metamorphosis.
Authors: Regna Et al.
PLoS One 2016;16:15
A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response.
Authors: FitzGerald Et al.
PLoS One 2014;9:e98891
First and second generation antipsychotics influence hippocampal gamma oscillations by interactions with 5-HT3 and D3 receptors.
Authors: Schulz Et al.
Br J Pharmacol 2012;167:1480
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