Catalog Number: 4057
Chemical Name: 4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride
Biological Activity
Antipsychotic drug. Exhibits antagonistic activity at dopamine D1-5 receptors. Used in schizophrenia treatment.

This compound is a mixture of E/Z isomers (ratio: 60:40).

Technical Data
  • M.Wt:
    507.44
  • Formula:
    C23H25F3N2OS.2HCl
  • Solubility:
    Soluble to 100 mM in water and to 50 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Desiccate at RT
  • CAS No:
    2413-38-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
  • This compound is a mixture of E/Z isomers (ratio: 60:40)
Background References
  1. Pharmacological properties of new antipsychotic agents: Use of animal models.
    Peuch et al.
    Neuropharmacology, 1981;20:1279
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Flupenthixol dihydrochloride include:

3 Citations: Showing 1 - 3
Filter your results:

  1. A critical role for the Drosophila dopamine D1-like receptor Dop1R2 at the onset of metamorphosis.
    Authors: Regna Et al.
    PLoS One 2016;16:15
  2. A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response.
    Authors: FitzGerald Et al.
    PLoS One 2014;9:e98891
  3. First and second generation antipsychotics influence hippocampal gamma oscillations by interactions with 5-HT3 and D3 receptors.
    Authors: Schulz Et al.
    Br J Pharmacol 2012;167:1480

Have you used Flupenthixol dihydrochloride?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information