Flupirtine maleate

  ( 1 citations )    
Product Datasheet
Catalog Number:2867
Alternate Names:D 9998
Chemical Name:N-[2-Amino-6-[[4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic acid ethyl ester maleate
Product Details
Citations (1)
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Reviews
Biological Activity
Non-opioid analgesic with muscle relaxant properties. Activates KV7 potassium channels, indirectly antagonizes NMDA receptors and modulates GABAA receptors. Exhibits neuroprotective actions in a model of cerebral ischemia in mice and reduces apoptosis and necrosis induced by noxious stimuli.

Deuterated analog also available.

Technical Data
  • M.Wt:
    420.4
  • Formula:
    C15H17FN4O2.C4H4O4
  • Solubility:
    Soluble to 100 mM in DMSO and to 10 mM in ethanol
  • Purity:
    >98
  • Storage:
    Desiccate at +4°C
  • CAS No:
    75507-68-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Flupirtine maleate include:

1 Citations: Showing 1 - 1

  1. Serum starvation-induced voltage-gated potassium channel Kv7.5 expression and its regulation by Sp1 in canine osteosarcoma cells.
    Authors: Lee Et al.
    Int J Mol Sci  2014;15:977

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