Catalog Number: 1033
Chemical Name: (E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone-O-(2-aminoethyl)oxime maleate
Biological Activity
Selective serotonin reuptake inhibitor; antidepressant. Binds to the human 5-HT transporter with a Ki of 1.6 nmol/l.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 10 mM in water
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Fluvoxamine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness.
    Benfield and Ward
    Drugs, 1986;32:313
  2. Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor.
    Classen et al.
    Br.J.Pharmacol., 1977;60:505
  3. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites.
    Owens et al.
    J.Pharmacol.Exp.Ther., 1997;283:1305
  4. Interactions of selective serotonin reuptake inhibitors with subtypes of σ receptors in rat brain.
    Narita et al.
    Eur.J.Pharmacol., 1996;307:117
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