Catalog Number: 5461
Biological Activity
Wnt5a peptide mimetic. Impairs migration and invasion of 4T1 breast cancer cells in vitro. Also inhibits metastasis of inoculated 4T1 cells in mice.
Technical Data
  • M.Wt:
    694.77
  • Formula:
    C26H42N6O12S2
  • Sequence:
    MDGCEL

    (Modifications: Met-1 = N-Formyl)

  • Solubility:
    Soluble to 1 mg/ml in PBS (pH 7.4)
  • Storage:
    Store at -20°C
  • CAS No:
    881188-51-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells.
    Säfholm et al.
    J.Biol.Chem., 2006;281:2740
  2. The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility.
    Säfholm et al.
    Clin.Cancer Res., 2008;14:6556

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