G10

Catalog # Availability Size / Price Qty
5944/10
5944/50
Cat.No. 5944 - G10 | C21H16ClFN2O3S | CAS No. 702662-50-8
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Description: Activator of STING-dependent signaling

Chemical Name: 4-[(2-Chloro-6-fluorophenyl)methyl]-N-(2-furanylmethyl)-3,4-dihydro-3-oxo-2H-1,4-benzothiazine-6-carboxamide

Purity: ≥98%

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Biological Activity

Activator of STING-dependent signaling; exhibits no direct binding affinity for STING. Stimulates IRF-3-induced transcription and induces IFNα and IFNγ gene expression in human fibroblasts. Exhibits no effect on NF-κB signaling. Blocks viral replication in vitro.

Technical Data

M.Wt:
430.88
Formula:
C21H16ClFN2O3S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
702662-50-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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