Aminoglycosidic antibiotic. Inhibits protein synthesis in both prokaryotic and eukaryotic cells. Used for selection of eukaryotic cells transfected with the neo
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Antibiotic G-418, a new Micromonospora-produced aminoglycoside with activity against protozoa and helminths: fermentation, isolation and preliminary characterization.
Wagman et al.
Antimicrob.Agents Chemother., 1974;6:144
G-418, an elongation inhibitor of 80 S ribosomes.
Bar-Nun et al.
Suppression of a nonsense mutation in mammalian cells in vivo by the aminoglycoside antibiotics G-418 and paromomycin.
Burke and Mogg
Nucleic Acids Res., 1985;13:6265