Galidesivir dihydrochloride

Catalog # Availability Size / Price Qty
7229/2
Galidesivir dihydrochloride | CAS No. 1373208-51-5 | RNA/DNA Polymerase Inhibitors
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Description: Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral
Alternative Names: BCX 4430

Chemical Name: (2S,3S,4R,5R)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)-3,4-pyrrolidinediol dihydrochloride

Purity: ≥98%

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Biological Activity

Galidesivir is a viral RNA-dependent RNA polymerase (RdRP) inhibitor and broad spectrum antiviral nucleotide. In vitro, galidesivir displays antiviral activity against a range of RNA viruses, including bunyaviruses, arenaviruses, paramyxoviruses, coronaviruses, and flaviviruses (EC50 values range from 3 μM to >100 μM). Galidesivir protects against Ebola and Marburg viral infection in animal models.

Technical Data

M.Wt:
338.19
Formula:
C11H15N5O3.2HCl
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1373208-51-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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