Galidesivir dihydrochloride

Key Product Details

Product Description

Galidesivir is a viral RNA-dependent RNA polymerase (RdRP) inhibitor and broad spectrum antiviral nucleotide. In vitro, galidesivir displays antiviral activity against a range of RNA viruses, including bunyaviruses, arenaviruses, paramyxoviruses, coronaviruses, and flaviviruses (EC₅₀ values range from 3 μM to >100 μM). Galidesivir protects against Ebola and Marburg viral infection in animal models.

Product Specifications for Galidesivir dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Galidesivir dihydrochloride

The following data is based on the product molecular weight 338.19.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.96 mL	14.78 mL	29.57 mL
5 mM	0.59 mL	2.96 mL	5.91 mL
10 mM	0.30 mL	1.48 mL	2.96 mL
50 mM	0.06 mL	0.30 mL	0.59 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Warren Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430. Nature. 2014 PMID: 24590073
• Li & De Clercq Therapeutic options for the 2019 novel coronavirus (2019-nCoV). Nat.Rev.Drug Discov. 2020 PMID: 32127666

Product Documents for Galidesivir dihydrochloride