Galnon

  ( 1 citations )    
Product Datasheet
Catalog Number:2085
Chemical Name:3-Cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide
Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity
Novel non-peptide galanin GAL1 and GAL2 receptor agonist (Ki values are 11.7 and 34.1 μM respectively). Stimulates insulin release in isolated pancreatic islets from normal and diabetic rats. Systemically active in vivo; displays anticonvulsant activity following i.p. administration in mice. Central and peripheral administration also transiently inhibits food intake in rats and mice.
Technical Data
  • M.Wt:
    678.83
  • Formula:
    C40H46N4O6
  • Sequence:
    AK

    (Modifications: Ala-1 = Fmoc-β-cyclohexyl-Ala, Lys-2 = Lys-(4-methyl-2-oxo-2H-1-benzopyran)

  • Solubility:
    Soluble to 67.88 mg/ml in DMSO and to 16.97 mg/ml in ethanol with gentle warming
  • Storage:
    Desiccate at -20°C
  • CAS No:
    475115-35-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Galnon include:

1 Citations: Showing 1 - 1

  1. Galanin-induced decreases in nucleus accumbens/striatum excitatory postsynaptic potentials and morphine conditioned place preference require both galanin receptor 1 and galanin receptor 2.
    Authors: Einstein Et al.
    Eur J Neurosci  2013;37:1541

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