Novel non-peptide galanin GAL1
receptor agonist (Ki
values are 11.7 and 34.1 μ
M respectively). Stimulates insulin release in isolated pancreatic islets from normal and diabetic rats. Systemically active in vivo
; displays anticonvulsant activity following i.p. administration in mice. Central and peripheral administration also transiently inhibits food intake in rats and mice.
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Regulation of feeding by galnon.
Abramov et al.
Anticonvulsant activity of a nonpeptide galanin receptor agonist
Saar et al.
A role for galanin in antidepressant actions with a focus on the dorsal raphe nucleus.
Lu et al.
Effects of galnon, a non-peptide galanin-receptor agonist, on insulin release from rat pancreatic islets.
Quynh et al.