Gap19

Catalog # Availability Size / Price Qty
5353/1
Gap19
1 Image
Description: Cx43 hemichannel blocker

Purity: ≥95%

Product Details
Citations (5)
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Biological Activity

Gap19 is a selective connexin 43 (Cx43) hemichannel blocker; has no effect on gap junction coupling or Panx-1 channels. Reduces mitochondrial potassium influx in cardiomyocytes and attenuates glutamate-triggered ATP release in primary astrocytes. Modestly reduces infarct size in a mouse ischemia model.

Technical Data

M.Wt:
1161.45
Formula:
C55H96N14O13
Sequence:
KQIEIKKFK
Solubility:
Soluble to 2 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
1507930-57-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Gap19

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