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GGsTop

4452 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4452/10

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GGsTop | CAS No. 926281-37-0 | Other Transferase Inhibitors
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Description: Inhibitor of γ-glutamyl transpeptidase (GGT)

Chemical Name: 3-[[(3-Amino-3-carboxypropyl)methoxyphosphinyl]oxy]benzeneacetic acid

Purity: ≥95%

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Biological Activity

GGsTop is a selective, irreversible γ-glutamyl transpeptidase (GGT) inhibitor; displays no inhibitory effects on glutamine amidotransferases or asparagine synthetase. Suppresses oxidative stress by inhibiting GGT activation. Prevents ischemia/reperfusion-induced acute kidney injury in rats in vivo.

Technical Data

M.Wt:
331.26
Formula:
C13H18NO7P
Solubility:
Soluble to 20 mM in water and to 50 mM in DMSO
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
926281-37-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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