Catalog # Availability Size / Price Qty
GGsTop | CAS No. 926281-37-0 | Other Transferase Inhibitors
1 Image
Description: Inhibitor of γ-glutamyl transpeptidase (GGT)

Chemical Name: 3-[[(3-Amino-3-carboxypropyl)methoxyphosphinyl]oxy]benzeneacetic acid

Purity: ≥95%

Product Details
Citations (2)

Biological Activity

GGsTop is a selective, irreversible γ-glutamyl transpeptidase (GGT) inhibitor; displays no inhibitory effects on glutamine amidotransferases or asparagine synthetase. Suppresses oxidative stress by inhibiting GGT activation. Prevents ischemia/reperfusion-induced acute kidney injury in rats in vivo.

Technical Data

Soluble to 20 mM in water and to 50 mM in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for GGsTop

The citations listed below are publications that use Tocris products. Selected citations for GGsTop include:

2 Citations: Showing 1 - 2

  1. Rapid fluorescent vital imaging of olfactory epithelium.
    Authors: Kenji Et al.
    iScience  2022;25:104222
  2. The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet.
    Authors: Elaine Y Et al.
    Cell  2018;173:1728-1741.e13


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