Chemical Name: 3-[[(3-Amino-3-carboxypropyl)methoxyphosphinyl]oxy]benzeneacetic acid
Biological ActivityGGsTop is a selective, irreversible γ-glutamyl transpeptidase (GGT) inhibitor; displays no inhibitory effects on glutamine amidotransferases or asparagine synthetase. Suppresses oxidative stress by inhibiting GGT activation. Prevents ischemia/reperfusion-induced acute kidney injury in rats in vivo.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Design, synthesis, and evaluation of γ-phosphono diester analogues of glutamate as highly potent inhibitors and active site probes of γ-glutamyl transpeptidase.
Han et al.
Preventive effect of GGsTop, a novel and selective γ-glutamyl transpeptidase inhibitor, on ischemia/reperfusion-induced renal injury in rats.
Yamamoto et al.
Citations for GGsTop
The citations listed below are publications that use Tocris products. Selected citations for GGsTop include:
2 Citations: Showing 1 - 2
Rapid fluorescent vital imaging of olfactory epithelium.
Authors: Kenji Et al.
The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet.
Authors: Elaine Y Et al.
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