Golgicide A

Key Product Details

Product Description

Golgicide A is a potent, specific and reversible inhibitor of Golgi BFA resistance factor 1 (GBF1), an ArfGEF, that decreases Arf1 activation in vivo. Arrests secretion of soluble and membrane-associated proteins at the endoplasmic reticulum-Golgi intermediate compartment. Causes disassembly and dispersal of the Golgi and trans-Golgi network.

Product Specifications for Golgicide A

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Golgicide A

The following data is based on the product molecular weight 284.30.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	7.03 mL	35.17 mL	70.35 mL
2.5 mM	1.41 mL	7.03 mL	14.07 mL
5 mM	0.70 mL	3.52 mL	7.03 mL
25 mM	0.14 mL	0.70 mL	1.41 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 15 publications citing the usage of this product.

• Saenz Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nature Chem.Biol.

Product Documents for Golgicide A