GR 203040

Catalog # Availability Size / Price Qty
4647/25
4647/5
Cat.No. 4647 - GR 203040 | C20H24N6O.2HCl | CAS No. 168398-02-5
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Description: Potent and selective NK1 antagonist

Chemical Name: (2S,3S)-N-[[2-Methoxy-5-(1H-tetrazol-1-yl)phenyl]methyl]-2-phenyl-3-piperidinamine dihydrochloride

Purity: ≥98%

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Biological Activity

Potent and selective NK1 receptor antagonist. Potently inhibits substance P binding to NK1 receptors (pKi = 10.1 to 10.5). Displays antiemetic activity in vivo.

Technical Data

M.Wt:
437.37
Formula:
C20H24N6O.2HCl
Solubility:
Soluble to 20 mM in water and to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
168398-02-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline

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