Biological ActivityGR 73632 is a potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens). Active in vivo.
(Modifications: Phe-1 = delta-Aminovaleryl-Phe, Leu-4 = (methyl)Leu, Met-5 = C-terminal amide)
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Novel ligands confirm NK-1 receptor-mediated modulation of neurotransmission in the guinea pig vas deferens preparation.
Hall and Morton
GR 73,632 and [glu(OBzl)11]substance P are selective agonists for the septide-sensitive tachykinin NK1 receptor in the rat urinary bladder.
Meini et al.
Spinal actions of GR73632, a novel tachykinin NK1 receptor agonist.
Sakurada et al.
Citations for GR 73632
The citations listed below are publications that use Tocris products. Selected citations for GR 73632 include:
5 Citations: Showing 1 - 5
Direct actions of kisspeptins on GnRH neurons permit attainment of fertility but are insufficient to fully preserve gonadotropic axis activity.
Authors: León Et al.
Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity.
Authors: León Et al.
The integrated hypothalamic tachykinin-kisspeptin system as a central coordinator for reproduction.
Authors: Navarro Et al.
Mol Psychiatry 2015;156:627
Effects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult rats.
Authors: Ruiz-Pino Et al.
TRPA1 controls inflammation and pruritogen responses in allergic contact dermatitis.
Authors: Liu Et al.
FASEB J 2013;27:3549
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