Catalog Number: 4581
Chemical Name: 2,4-Dihydroxy-6-methyl-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-benzoic acid
Biological Activity
Selective partial FFA4 (GPR120) agonist. Induces ERK and [Ca2+]i responses in cells expressing GPR120, but not those expressing GPR40.
Technical Data
  • M.Wt:
    372.5
  • Formula:
    C23H32O4
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    80557-12-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Novel selective ligands for free fatty acid receptors GPR120 and GPR40.
    Hara et al.
    Naunyn Schmiedebergs Arch.Pharmacol., 2009;380:247
  2. Structure-activity relationships of GPR120 agonists based on a docking simulation.
    Sun et al.
    Mol.Pharmacol., 2010;78:804

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