Chemical Name: 2,4-Dihydroxy-6-methyl-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-benzoic acid
Biological ActivitySelective partial FFA4 (GPR120) agonist. Induces ERK and [Ca2+]i responses in cells expressing GPR120, but not those expressing GPR40.
The technical data provided above is for guidance only.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Novel selective ligands for free fatty acid receptors GPR120 and GPR40.
Hara et al.
Naunyn Schmiedebergs Arch.Pharmacol., 2009;380:247
Structure-activity relationships of GPR120 agonists based on a docking simulation.
Sun et al.
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