GS 39783

  ( 2 citations )    
Product Datasheet
Catalog Number:2001
Chemical Name:N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine
Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity
Positive allosteric modulator of GABAB receptor function. Potentiates the effects of GABA on [35S]GTPγS binding at recombinant and native GABAB receptors (EC50 values are 2.1 and 3.1μM respectively). Decreases cocaine self-administration, blocks the rewarding properties of nicotine and produces anxiolytic-like activity without the side effects associated with baclofen or benzodiazepines.
Technical Data
  • M.Wt:
    337.44
  • Formula:
    C15H23N5O2S
  • Solubility:
    Soluble to 5 mM in ethanol and to 10 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    39069-52-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for GS 39783 include:

2 Citations: Showing 1 - 2
Filter your results:

  1. GABAB receptor upregulates fragile X mental retardation protein expression in neurons.
    Authors: Zhang Et al.
    Sci Rep  2015;5:10468
  2. Subchronic administration and combination metabotropic glutamate and GABAB receptor drug therapy in fragile X syndrome.
    Authors: Pacey Et al.
    Sci Rep  2011;338:897

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used GS 39783?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee