Chemical Name: 4-[[(1-Hexyl-1,2-dihydro-2-oxo-3-quinolinyl)carbonyl]amino]benzoic acid propyl ester
Biological Activity Smoothened (Smo) receptor agonist (EC50 = 1.2 μM). Does not recognize the classic cyclopamine (Cat. No. 1623) binding site. Does not promote Smo translocation to the primary cilium; is strongly potentiated by forskolin and cholera toxin. Promotes differentiation of multipotent mesenchymal progenitor cells into osteoblasts.
Soluble to 5 mM in DMSO with gentle warming
Store at +4°C
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