GSK 264220A

Key Product Details

Product Description

GSK 264220A is an endothelial lipase and lipoprotein lipase inhibitor (IC₅₀ values are 0.13 and 0.10 μM respectively).

Product Specifications for GSK 264220A

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for GSK 264220A

The following data is based on the product molecular weight 363.43.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.75 mL	13.76 mL	27.52 mL
5 mM	0.55 mL	2.75 mL	5.50 mL
10 mM	0.28 mL	1.38 mL	2.75 mL
50 mM	0.06 mL	0.28 mL	0.55 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

• Goodman Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors. Bioorg.Med.Chem.Letts.
• Keller A high-throughput screen for the endothelial lipase using HDL as substrate. J.Biomol.Screen. 2008 PMID: 18566479

Product Documents for GSK 264220A