GSK 3787
Chemical Name: 4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide
Purity: ≥99%
Biological Activity
Potent and selective peroxisome proliferator-activated receptor δ (PPARδ) antagonist (pIC50 = 6.6). Displays no measurable affinity for PPARα or PPARγ in vitro (pIC50< 5).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Identification and characterization of 4-chloro-N(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist.
Shearer et al.
J.Med.Chem., 2010;53:1857 -
Cellular and pharmacological selectivity of the peroxisone proliferator-activated receptor-β/δ antagonist GSK3787.
Palkar et al.
Mol.Pharmacol., 2010;78:419
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citation for GSK 3787
The citations listed below are publications that use Tocris products. Selected citations for GSK 3787 include:
1 Citation: Showing 1 - 1
-
PPARδ signaling mediates the cytotoxicity of DHA in H9c2 cells.
Authors: Samokhvalov Et al.
Cell Cycle 2015;232:44105
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsVersaClone cDNA Plasmids
Reviews for GSK 3787
There are currently no reviews for this product. Be the first to review GSK 3787 and earn rewards!
Have you used GSK 3787?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
