GSK 9027

Key Product Details

Product Description

GSK 9027 is a glucocorticoid receptor agonist (pIC₅₀ = 8). Inhibits production of the proinflammatory mediator IL-6 in vivo.

Licensing Information

Sold for research purposes under agreement from GlaxoSmithKline.

Product Specifications for GSK 9027

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for GSK 9027

The following data is based on the product molecular weight 525.52.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.90 mL	9.51 mL	19.03 mL
5 mM	0.38 mL	1.90 mL	3.81 mL
10 mM	0.19 mL	0.95 mL	1.90 mL
50 mM	0.04 mL	0.19 mL	0.38 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Yates Structure guided design of 5-arylindazole glucocorticoid receptor agonists and antagonists. J.Med.Chem. 2010 PMID: 20469868

Product Documents for GSK 9027