Biological Activity Selective EAAT2 positive allosteric modulator (EC50 = 0.26 nM). Enhances the glutamate translocation rate, with no effect on substrate interaction. Enhances glutamate uptake by cultured astrocytes by approximately 58%. Exhibits no effect on DAT, SERT and NET or NMDA receptors.
Soluble to 100 mM in DMSO
Store at -20°C
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